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Recently, a lot of Chinese patients consult treatment plans through social networking platforms, but the Chinese medical text contains rich information, including a large number of medical nomenclatures and symptom descriptions. How to build an intelligence model to automatically classify the text information consulted by patients and recommend the correct department for patients is very important. In order to address the problem of insufficient feature extraction from Chinese medical text and low accuracy, this paper proposes a dual channel Chinese medical text classification model. The model extracts feature of Chinese medical text at different granularity, comprehensively and accurately obtains effective feature information, and finally recommends departments for patients according to text classification. One channel of the model focuses on medical nomenclatures, symptoms and other words related to hospital departments, gives different weights, calculates corresponding feature vectors with convolution kernels of different sizes, and then obtains local text representation. The other channel uses the BiGRU network and attention mechanism to obtain text representation, highlighting the important information of the whole sentence, that is, global text representation. Finally, the model uses full connection layer to combine the representation vectors of the two channels, and uses Softmax classifier for classification. The experimental results show that the accuracy, recall and F1-score of the model are improved by 10.65%, 8.94% and 11.62% respectively compared with the baseline models in average, which proves that our model has better performance and robustness.

This article discusses the new gaming law in Macau with emphasis on the critical aspects concerning the gaming operators, concession regime, and other regulatory obligations.1 Thanks to the gaming liberalization commenced in 2001,2 Macau has experienced tremendous economic growth. The past two decades have seen the rapid development of large-scale integrated resorts, and Macau now ranks among the world's major gaming jurisdictions.3 Policy and regulatory challenges have also emerged along with the growth of the junket-driven VIP business in casinos.4 With the recent amendment of Law No. 16/2001 and the subsequent enactment of Law No. 16/2022, Macau has strengthened the legal underpinnings of its system of gaming regulation to oversee various groups involved in casinos and their industry practices. The present study is among the first to review the scope and impact of the revised gaming law, and associated managerial and operational implications for Macau casinos. Topics covered include policy directions, concession requirements, industry participants, gaming taxes, and fair business practices. This study could provide insights into the “Macau 2.0” project and how casinos are to be operated and managed over the next decade. This article could also provide practical guidance for policy makers charged with formulating gaming policy and regulation in other jurisdictions.

The extraction of 21 insecticides and 5 metabolites was performed using an optimized and validated QuEChERS protocol that was further used for the quantification (GC–MS/MS) in several seafood matrices (crustaceans, bivalves, and fish-mudskippers). Seven species, acquired from Hong Kong and Macao wet markets (a region so far poorly monitored), were selected based on their commercial importance in the Indo-Pacific region, market abundance, and affordable price. Among them, mussels from Hong Kong, together with mudskippers from Macao, presented the highest insecticide concentrations (median values of 30.33 and 23.90 ng/g WW, respectively). Residual levels of fenobucarb, DDTs, HCHs, and heptachlors were above the established threshold (10 ng/g WW) for human consumption according to the European and Chinese legislations: for example, in fish-mudskippers, DDTs, fenobucarb, and heptachlors (5-, 20- and tenfold, respectively), and in bivalves, HCHs (fourfold) had higher levels than the threshold. Risk assessment revealed potential human health effects (e.g., neurotoxicity), especially through fish and bivalve consumption (non-carcinogenic risk; ΣHQLT > 1), and a potential concern of lifetime cancer risk development through the consumption of fish, bivalves, and crustaceans collected from these markets (carcinogenic risk; ΣTCR > 10–4). Since these results indicate polluted regions, where the seafood is collected/produced, a strict monitoring framework should be implemented in those areas to improve food quality and safety of seafood products.

Employees work long hours in an environment where the ambient air quality is poor, directly affecting their work efficiency. The concentration of particulate matters (PM) produced by the interior renovation of shopping malls has not received particular attention in Macao. Therefore, this study will investigate the indoor air quality (IAQ), in particular of PM2.5, in large-scale shopping mall renovation projects. This study collected on-site PM data with low-cost portable monitoring equipment placed temporarily at specific locations to examine whether the current control measures are appropriate and propose some improvements. Prior to this study, there were no measures being implemented, and on-site monitoring to assess the levels of PM2.5 concentrations was non-existent. The results show the highest level of PM2.5 recorded in this study was 559.00 μg/m3. Moreover, this study may provide a reference for decision-makers, management, construction teams, design consultant teams, and renovation teams of large-scale projects. In addition, the monitoring of IAQ can ensure a comfortable environment for employees and customers. This study concluded that the levels of PM2.5 concentration have no correlation with the number of on-site workers, but rather were largely influenced by the processes being performed on-site.

Macau has long been considered to be an example of remarkable economic growth. With the opening of the gaming sector in 2002, the casino and hospitality sector flourished, creating employment opportunities but also imposing several challenges on managers. Since Macau endeavors to be positioned as the center for international business with Portuguese-speaking countries and a platform for trading with China’s Greater Bay Area (GBA), it becomes essential for international enterprises to understand the local dynamics. In light of the limited research available, this study aims to identify management challenges from the perspectives of senior executives in different industries based in Macau. Our findings point out that managers must contend with several issues, such as the lack of a skilled local talent pool, high turnover rates, employees' work attitudes, and a tightly controlled immigration policy. It is also imperative for international managers to nurture relationships and pay attention to the local culture. Our results suggest that Macau has to develop a highly skilled local workforce to attract international companies, while local organizations also have to create an attractive working environment to compete in the marketplace.

The adoption of project management techniques is a crucial decision for corporate governance in construction companies since the management of areas such as risk, cost, and communications is essential for the success or failure of an endeavor. Nevertheless, different frameworks based on traditional or agile methodologies are available with several approaches, which may create several ways to manage projects. The primary purpose of this work is to investigate the adequate project management methodology for the construction industry from a general perspective and consider a case study from Macau. The methodology considered semi-structured interviews and a survey comparing international and local project managers from the construction industry. The interviews indicate that most construction project managers still follow empirical methods with no specific methodology but consider the adoption of traditional waterfall approaches. In contrast, according to the survey, most project managers and construction managers agree that the project's efficacy needs to increase, namely in planning, waste minimization, communication increase, and focus on the Client's feedback. In addition, there seems to be a clear indication that agile methodology could be implemented in several types of projects, including hospitality development projects. A hybrid development approach based on the Waterfall and Agile methodologies as a tool for the project management area may provide a more suitable methodology for project managers to follow.

Objective: Over the past decade, arbitration has grown in popularity as a method of resolving commercial disputes worldwide. However, this practice is relatively new in Macao SAR. Recently, official plans were announced to make Macao as a seat of arbitration for commercial disputes between China and Portuguese-speaking countries (Hereinafter PSCs). This article is dedicated to explores the possibility of Macao undertaking and implementing such a role. Accordingly, this article addresses the following issues: What are the strengths and weaknesses of Macao as a seat and eventually as venue for hosting international commercial arbitration between Chinese and PSCs entrepreneurs?Methodology: A mixed-method approach of legal doctrinal and empirical research was used in this article. We first included a thorough study of the concept of arbitration followed by analysis of various legal journals and legislations, including Macao, China, and PSCs’ arbitration laws. An empirical research was then used to collect data by surveying and interviewing with both lawyers and arbitration practitioners from Macao, China and PSCs.Results: This article argues that the strength of Macao resides in the similarities between its legal system and that of the China and PSCs and the languages advantage (Chinese and Portuguese both official languages). In spite of this, arbitration is still relatively underutilized in the region, and there is a limited number of arbitrators and legal professionals with bilingual proficiency.Contributions: This article contributes to the identification of the opportunities and challenges that Macao faces in its potential future development as a seat/venue of arbitration between China and the PSCs.

Since the beginning of 2020, Coronavirus Disease 19 (COVID-19) has attracted the attention of the World Health Organization (WHO). This paper looks into the infection mechanism, patient symptoms, and laboratory diagnosis, followed by an extensive assessment of different technologies and computerized models (based on Electrocardiographic signals (ECG), Voice, and X-ray techniques) proposed as a diagnostic tool for the accurate detection of COVID-19. The found papers showed high accuracy rate results, ranging between 85.70% and 100%, and F1-Scores from 89.52% to 100%. With this state-of-the-art, we concluded that the models proposed for the detection of COVID-19 already have significant results, but the area still has room for improvement, given the vast symptomatology and the better comprehension of individuals’ evolution of the disease.

Parental nutrient reserves are directly related to reproductive performance in sea cucumbers. This study focused on the lipid requirements of male and female sea cucumbers Apostichopus japonicus during the reproductive stage and analyzed their physiological responses to a high-fat diet (HFD). The intestinal lipid metabolites and microbiome profile changed significantly in animals fed with the HFD, as given by an upregulation of metabolites related to lipid metabolism and an increase in the predominance of Proteobacteria in the microbiome, respectively. The metabolic responses of male and female sea cucumbers to the HFD differed, which in turn could have triggered sex-related differences in the intestinal microbiome. These results suggest that the lipid content in diets can be differentially adjusted for male and female sea cucumbers to improve nutrition and promote reproduction. This data contributes to a better understanding of the reproductive biology and sex differences of sea cucumbers.

Reproduction of the sea cucumber Apostichopus japonicus is critical for aquaculture production. Gonadal development is the basis of reproduction, and lipids, which are among the main nutrients required for gonadal development, directly affect reproduction. We investigated whether gonadal and intestinal lipid metabolism differed between male and female A. japonicus. Transcriptome analysis of the intestines of sexually mature male and female wild-caught individuals revealed differences in gene expression, with 27 and 39 genes being up-regulated in females and males, respectively. In particular, the expression of the fatty acid synthase gene was higher in males than in females. Metabolome analysis of the gonads identified 141 metabolites that were up-regulated and 175 metabolites that were down-regulated in the testes compared with the ovaries in the positive/negative mode of an LC-MS/MS analysis. A variety of polyunsaturated fatty acids were found at higher concentrations in the testes than in the ovaries. 16 s rDNA sequencing analysis showed that the composition and structure of the intestinal microbiota were similar between males and females. These results suggest that sex differences in intestinal metabolism of A. japonicus are not due to differences in the microbiota, and we speculate that gonadal metabolism may be related to intestinal morphology. This information might be useful in improving the reproductive efficiency of sea cucumbers in captivity.

Reaction of ultramafic rocks with seawater and subsequent serpentinization has been considered one of the most important factors controlling the formation of ultramafic-hosted seafloor massive sulfide (UM-SMS) deposits. However, the mineralization processes responsible for these deposits remain poorly understood, in particular because they are less abundant as compared with their basaltic counterparts. In this work, serpentinites with different alteration grades collected at the Tianzuo hydrothermal field (THF), Southwest Indian Ridge, were studied. Mineralogical and chemical analyses were performed in the secondary opaque minerals resulting from serpentinization to understand the role of this process during the formation of UM-SMS deposits. Our results show that these opaque minerals mainly consist of magnetite, hematite, pentlandite, and minor pyrite, suggestive of high but varying oxygen and sulfur fugacities. The hematite is characterized by an enrichment in Mg, Si, Ni, and Co as compared with magnetite. Pentlandite associated with hematite has elevated and consistent Ni contents as compared with that associated with magnetite. These results indicate that breakdown and decomposition of primary silicate and sulfide minerals during serpentinization has controlled the sources of ore-forming materials. Concentrations of Te are variable and show a positive correlation with Ni in pentlandite associated with magnetite or hematite, suggesting that gabbroic intrusions provided additional material to the hydrothermal system. Oxidation and sulfidation conditions are ideal for the formation of trisulfur ion S3− in THF, which can significantly improve the capability of hydrothermal fluids for leaching ore-forming metals from the wall rocks, promoting the formation of THF. In addition of reduced systems, hydrothermal fluids with high oxygen and sulfur fugacities triggered by extensive seawater infiltration can most likely also develop in ultramafic-hosted systems. These results suggest that the areas with well-developed fractures are promising candidates for further exploration of UM-SMS deposits along mid-oceanic ridges.

Electronic government is increasingly dominant in the study of public administration. In analysing people's behavioural factors towards the adoption of e-services, most previous studies targeted the adult population, while those on government employees are minimal. Government employees have an essential function in the process of government operation; they can be regarded as the principal medium of communication between the service provider (government) and the end-users (citizens). This study was designed to understand the government employees' behavioural factors on their intentions towards adopting e-government services. A set of semi-structured interview questions was developed based on the prior literature on the Theory of Planned Behaviour (TPB) and e-government studies. Ten in-depth interviews were conducted in Macao SAR (Special Administrative Region). In addition to analysing the three primary constructs of TPB, the factor of Trust and some enablers and hindrances were identified. Significant findings were yielded while investigating how the government employees perceived the e-services and how they regarded the general public's perception of this issue. This contextualisation would help policymakers look at this issue from different perspectives and design feasible interventions according to group alignment strategies.

The objective of this case study is to analyze how two groups of parents, a group who have newly arrived in Macau from Mainland China and the other who have resided in Macau for more than three decades, interact with the class teachers at the levels of ?two-way communication,? ?supervision of children at home,? and ?participating in decision making? in a secondary school. The findings will redound to the benefits of school leaders, teachers, and indirectly the parents in a sense that looking closely at the ethnic and cultural differences between parents can promote effective cooperation between parents and teachers.

Air pollution in Macau has become a serious problem following the Pearl River Delta’s (PRD) rapid industrialization that began in the 1990s. With this in mind, Macau needs an air quality forecast system that accurately predicts pollutant concentration during the occurrence of pollution episodes to warn the public ahead of time. Five different state-of-the-art machine learning (ML) algorithms were applied to create predictive models to forecast PM2.5, PM10, and CO concentrations for the next 24 and 48 h, which included artificial neural networks (ANN), random forest (RF), extreme gradient boosting (XGBoost), support vector machine (SVM), and multiple linear regression (MLR), to determine the best ML algorithms for the respective pollutants and time scale. The diurnal measurements of air quality data in Macau from 2016 to 2021 were obtained for this work. The 2020 and 2021 datasets were used for model testing, while the four-year data before 2020 and 2021 were used to build and train the ML models. Results show that the ANN, RF, XGBoost, SVM, and MLR models were able to provide good performance in building up a 24-h forecast with a higher coefficient of determination (R2) and lower root mean square error (RMSE), mean absolute error (MAE), and biases (BIAS). Meanwhile, all the ML models in the 48-h forecasting performance were satisfactory enough to be accepted as a two-day continuous forecast even if the R2 value was lower than the 24-h forecast. The 48-h forecasting model could be further improved by proper feature selection based on the 24-h dataset, using the Shapley Additive Explanations (SHAP) value test and the adjusted R2 value of the 48-h forecasting model. In conclusion, the above five ML algorithms were able to successfully forecast the 24 and 48 h of pollutant concentration in Macau, with the RF and SVM models performing the best in the prediction of PM2.5 and PM10, and CO in both 24 and 48-h forecasts.

<abstract><p>About 6.5 million people are infected with Chagas disease (CD) globally, and WHO estimates that $ &gt; million people worldwide suffer from ChHD. Sudden cardiac death (SCD) represents one of the leading causes of death worldwide and affects approximately 65% of ChHD patients at a rate of 24 per 1000 patient-years, much greater than the SCD rate in the general population. Its occurrence in the specific context of ChHD needs to be better exploited. This paper provides the first evidence supporting the use of machine learning (ML) methods within non-invasive tests: patients' clinical data and cardiac restitution metrics (CRM) features extracted from ECG-Holter recordings as an adjunct in the SCD risk assessment in ChHD. The feature selection (FS) flows evaluated 5 different groups of attributes formed from patients' clinical and physiological data to identify relevant attributes among 57 features reported by 315 patients at HUCFF-UFRJ. The FS flow with FS techniques (variance, ANOVA, and recursive feature elimination) and Naive Bayes (NB) model achieved the best classification performance with 90.63% recall (sensitivity) and 80.55% AUC. The initial feature set is reduced to a subset of 13 features (4 Classification; 1 Treatment; 1 CRM; and 7 Heart Tests). The proposed method represents an intelligent diagnostic support system that predicts the high risk of SCD in ChHD patients and highlights the clinical and CRM data that most strongly impact the final outcome.</p></abstract>

In view of the complex marine environment of navigation, especially in the case of multiple static and dynamic obstacles, the traditional obstacle avoidance algorithms applied to unmanned surface vehicles (USV) are prone to fall into the trap of local optimization. Therefore, this paper proposes an improved artificial potential field (APF) algorithm, which uses 5G communication technology to communicate between the USV and the control center. The algorithm introduces the USV discrimination mechanism to avoid the USV falling into local optimization when the USV encounter different obstacles in different scenarios. Considering the various scenarios between the USV and other dynamic obstacles such as vessels in the process of performing tasks, the algorithm introduces the concept of dynamic artificial potential field. For the multiple obstacles encountered in the process of USV sailing, based on the International Regulations for Preventing Collisions at Sea (COLREGS), the USV determines whether the next step will fall into local optimization through the discrimination mechanism. The local potential field of the USV will dynamically adjust, and the reverse virtual gravitational potential field will be added to prevent it from falling into the local optimization and avoid collisions. The objective function and cost function are designed at the same time, so that the USV can smoothly switch between the global path and the local obstacle avoidance. The simulation results show that the improved APF algorithm proposed in this paper can successfully avoid various obstacles in the complex marine environment, and take navigation time and economic cost into account.