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<abstract><p>About 6.5 million people are infected with Chagas disease (CD) globally, and WHO estimates that $ > million people worldwide suffer from ChHD. Sudden cardiac death (SCD) represents one of the leading causes of death worldwide and affects approximately 65% of ChHD patients at a rate of 24 per 1000 patient-years, much greater than the SCD rate in the general population. Its occurrence in the specific context of ChHD needs to be better exploited. This paper provides the first evidence supporting the use of machine learning (ML) methods within non-invasive tests: patients' clinical data and cardiac restitution metrics (CRM) features extracted from ECG-Holter recordings as an adjunct in the SCD risk assessment in ChHD. The feature selection (FS) flows evaluated 5 different groups of attributes formed from patients' clinical and physiological data to identify relevant attributes among 57 features reported by 315 patients at HUCFF-UFRJ. The FS flow with FS techniques (variance, ANOVA, and recursive feature elimination) and Naive Bayes (NB) model achieved the best classification performance with 90.63% recall (sensitivity) and 80.55% AUC. The initial feature set is reduced to a subset of 13 features (4 Classification; 1 Treatment; 1 CRM; and 7 Heart Tests). The proposed method represents an intelligent diagnostic support system that predicts the high risk of SCD in ChHD patients and highlights the clinical and CRM data that most strongly impact the final outcome.</p></abstract>
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The difficult task of innovation is a key facet of Research & Development (R&D) institutions. To Design, innovation is to make the project technically feasible, economically viable, merchandising interesting and emotionally engaging. Design Thinking integrated with R&D organizations can foster the relationship between Universities and new markets. By addressing these topics, this book researches new emerging design methods and provide an overview of Design Thinking tools that can be applied in an early stage of the R&D research process to produce meaningful results. It is taken into account that design, through Design Thinking, extends to the experience that costumers/users have with products/services or even multidimensional experiences, which is a relevant input for R&D innovation development. In fact, the establishment of coherent guidelines for the Design Thinking process is a very complex task, due to its interdisciplinary requirements, that convey many diverse mindsets. The main focus of this book is creating an analysis toolkit that enables non-specialist and specialist users to perform high-quality design solutions.
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O presente estudo faz parte de uma investigação mais alargada que pretende i) estudar, numa população estudantil de ensino superior, as suas necessidades e comportamento perante a informação e ii) desenvolver um programa de formação em literacia da informação, integrando este conhecimento e os contributos dos diversos intervenientes (estudantes, docentes, bibliotecários). Sabemos hoje que a integração da literacia da informação nas aprendizagens melhora o desempenho dos estudantes e que, por esse motivo, os bibliotecários académicos podem desempenhar um papel importante ao colaborarem no desenho e formação de programas nestas áreas. Esta comunicação apresenta a primeira fase deste estudo. Trata-se da aplicação de um inquérito por questionário a uma população de estudantes de graduação, no ensino superior, em Macau. Os resultados demonstram as perceções dos estudantes relativamente às suas necessidades de informação, bem como o uso dos recursos informativos preferidos na prossecução dos seus estudos. A formação destes estudantes na pesquisa, recuperação, análise e uso da informação parece ser essencial. A construção de programas de formação em literacia da informação deve ser concebida à medida, recorrendo-se a um diagnóstico próximo e efetivo. A par, é importante continuar a desenvolver ambientes físicos e virtuais que disponibilizem informação credível e que deem resposta às necessidades informacionais dos que os utilizam, apoiando a aprendizagem.
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