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The pathophysiological mechanisms of arterial hypertension during hemodialysis (HD) in patients with end-stage renal disease (ESRD) are still poorly understood. The aim of this study is to investigate physiological, cardiovascular and neuroendocrine changes in patients with ESRD and its correlation with changes in blood pressure (BP) during the HD session. The present study included 21 patients with ESRD undergoing chronic HD treatment. Group A (study) consisted of patients who had BP increase and group B (control) consisted of those who had BP reduction during HD session. Echocardiograms were performed during the HD session to evaluate cardiac output (CO) and systemic vascular resistance (SVR). Before and after the HD session, blood samples were collected to measure brain natriuretic peptide (BNP), catecholamines, endothelin-1 (ET-1), nitric oxide (NO), electrolytes, hematocrit, albumin and nitrogen substances. The mean age of the studied patients was 43±4.9 years, and 54.6% were males. SVR significantly increased in group A (P<0.001). There were no differences in the values of BNP, NO, adrenalin, dopamin and noradrenalin, before and after dialysis, between the two groups. The mean value of ET-1, post HD, was 25.9 pg ml−1 in group A and 13.3 pg ml−1 in group B (P=<0.001). Patients with ESRD showed different hemodynamic patterns during the HD session, with significant BP increase in group A, caused by an increase in SVR possibly due to endothelial dysfunction, evidenced by an increase in serum ET-1 levels.
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We present an overview and discussion of the Colloquium «Narrative, Media and Cognition», which took place at Porto's Centre of Catholic University of Portugal in July of 2015, under the organization of the Research Centre for Science and Technology of the Arts (CITAR). Several scholars of different areas presented research about the uses and advances in narrative study and practice in a broad range of areas, giving some important insights about the latest developments in Narrative Studies, Ontology of Narrative and the uses of Narrative in Art, Cinema, Performance, Journalism, Marketing and Literature, among other fields. After briefly describing the main points of each presentation in the Colloquium we try to draw some conclusions and possibilities raised by the Colloquium and take a glimpse of future paths that the use of Narrative can end up taking.
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This paper presents an algorithm that applies metrics derived from automatic QRS detection and segmentation in electrocardiogram signals for analyzing Heart Rate Variability to study the evolution of metrics in the frequency domain of a clinical procedure. The analysis was performed on three sets of elderly people, who are categorized according to frailty phenotype. The first set was comprised of frail elderly, the second pre-frail elderly, and the third robust elderly. Investigators from many disciplines have been encouraged to contribute to the understanding of molecular and physiological changes in multiple systems that may increase the vulnerability of frail elderly. In this work, the frailty phenotype can be characterized by unintentional weight loss, as self-reported, fatigue assessed by self-report, grip strength (measured directly), physical activity level assessed by self-report and gait speed (measured). The results obtained demonstrate the existence of significant differences between Heart Rate Variability metrics for the three groups, especially considering a higher preponderance for sympathetic nervous system for the group of robust patients in response to postural maneuver.
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Vocal differentiation is widely documented in birds and mammals but has been poorly investigated in other vertebrates, including fish, which represent the oldest extant vertebrate group. Neural circuitry controlling vocal behaviour is thought to have evolved from conserved brain areas that originated in fish, making this taxon key to understanding the evolution and development of the vertebrate vocal-auditory systems. This study examines ontogenetic changes in the vocal repertoire and whether vocal differentiation parallels auditory development in the Lusitanian toadfish Halobatrachus didactylus (Batrachoididae). This species exhibits a complex acoustic repertoire and is vocally active during early development. Vocalisations were recorded during social interactions for four size groups (fry: <2 cm; small juveniles: 2–4 cm; large juveniles: 5–7 cm; adults >25 cm, standard length). Auditory sensitivity of juveniles and adults was determined based on evoked potentials recorded from the inner ear saccule in response to pure tones of 75–945 Hz. We show an ontogenetic increment in the vocal repertoire from simple broadband-pulsed ‘grunts’ that later differentiate into four distinct vocalisations, including low-frequency amplitude-modulated ‘boatwhistles’. Whereas fry emitted mostly single grunts, large juveniles exhibited vocalisations similar to the adult vocal repertoire. Saccular sensitivity revealed a three-fold enhancement at most frequencies tested from small to large juveniles; however, large juveniles were similar in sensitivity to adults. We provide the first clear evidence of ontogenetic vocal differentiation in fish, as previously described for higher vertebrates. Our results suggest a parallel development between the vocal motor pathway and the peripheral auditory system for acoustic social communication in fish.
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This study explores girls’ attitudes and selfassessment of abilities towards mathematics and science and its effects on career preferences. Results from Pi
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Religion and migration are both phenomena that have endured perennially in the experience of humanity. However, studies on the relationship of these two subjects are not as prevalent compared to how widespread international migration has become especially among people coming from religious societies. This work contributes to the knowledge base on the significance of religion within the context of international migration by looking at how religious faith and practice evolve as a result of the experience of migration. Interviews about the migration narratives of Filipino Catholics working in Macau were conducted. These were supported by data collected through the use of survey questionnaires that look into changes in religious practices of respondents as well as their attitudes towards faith and belief. The study has found that there is constancy in the religious faith and practice of Filipino Catholics even amidst external changes to the physical and social environment brought about by moving to a predominantly secular society. Through recourse to anthropological analysis, this immutability of faith is attributable to the unique ethnographic feature of Filipinos’ high regard for the centrality and importance of interiority in their life. Keywords: migration, immigrant religion, faith, Filipino religiosity
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