Machine learning-based cardiac activity non-linear analysis for discriminating COVID-19 patients with different degrees of severity
Resource type
Authors/contributors
- Ribeiro, Pedro (Author)
- Marques, João Alexandre Lobo (Author)
- Pordeus, Daniel (Author)
- Zacarias, Laíla (Author)
- Leite, Camila Ferreira (Author)
- Sobreira-Neto, Manoel Alves (Author)
- Peixoto, Arnaldo Aires (Author)
- de Oliveira, Adriel (Author)
- Madeiro, João Paulo do Vale (Author)
- Rodrigues, Pedro Miguel (Author)
Title
Machine learning-based cardiac activity non-linear analysis for discriminating COVID-19 patients with different degrees of severity
Abstract
Objective:
This study highlights the potential of an Electrocardiogram (ECG) as a powerful tool for early diagnosis of COVID-19 in critically ill patients with limited access to CT–Scan rooms.
Methods:
In this investigation, 3 categories of patient status were considered: Low, Moderate, and Severe. For each patient, 2 different body positions have been used to collect 2 ECG signals. Then, from each collected signal, 10 non-linear features (Energy, Approximate Entropy, Logarithmic Entropy, Shannon Entropy, Hurst Exponent, Lyapunov Exponent, Higuchi Fractal Dimension, Katz Fractal Dimension, Correlation Dimension and Detrended Fluctuation Analysis) were extracted every 1s ECG time-series length to serve as entries for 19 Machine learning classifiers within a leave-one-out cross-validation procedure. Four different classification scenarios were tested: Low vs. Moderate, Low vs. Severe, Moderate vs. Severe and one Multi-class comparison (All vs. All).
Results:
The classification report results were: (1) Low vs. Moderate - 100% of Accuracy and 100% of F1–Score; (2) Low vs. Severe - Accuracy of 91.67% and an F1–Score of 94.92%; (3) Moderate vs. Severe - Accuracy of 94.12% and an F1–Score of 96.43%; and (4) All vs All - 78.57% of Accuracy and 84.75% of F1–Score.
Conclusion:
The results indicate that the applied methodology could be considered a good tool for distinguishing COVID-19’s different severity stages using ECG signals.
Significance:
The findings highlight the potential of ECG as a fast and effective tool for COVID-19 examination. In comparison to previous studies using the same database, this study shows a 7.57% improvement in diagnostic accuracy for the All vs All comparison.
Publication
Biomedical Signal Processing and Control
Volume
87
Pages
105558
Date
2024-01-01
Journal Abbr
Biomedical Signal Processing and Control
ISSN
1746-8094
Accessed
1/14/24, 3:54 PM
Library Catalog
ScienceDirect
Citation
Ribeiro, P., Marques, J. A. L., Pordeus, D., Zacarias, L., Leite, C. F., Sobreira-Neto, M. A., Peixoto, A. A., de Oliveira, A., Madeiro, J. P. do V., & Rodrigues, P. M. (2024). Machine learning-based cardiac activity non-linear analysis for discriminating COVID-19 patients with different degrees of severity. Biomedical Signal Processing and Control, 87, 105558. https://doi.org/10.1016/j.bspc.2023.105558
Academic Units
United Nations SDGs
Cooperation
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