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"Peixoto, Arnaldo Aires"

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Ribeiro, P., Marques, J. A. L., Pordeus, D., Zacarias, L., Leite, C. F., Sobreira-Neto, M. A., Peixoto, A. A., de Oliveira, A., Madeiro, J. P. do V., & Rodrigues, P. M. (2024). Machine learning-based cardiac activity non-linear analysis for discriminating COVID-19 patients with different degrees of severity. Biomedical Signal Processing and Control, 87, 105558. https://doi.org/10.1016/j.bspc.2023.105558

Objective: This study highlights the potential of an Electrocardiogram (ECG) as a powerful tool for early diagnosis of COVID-19 in critically ill patients with limited access to CT–Scan rooms. Methods: In this investigation, 3 categories of patient status were considered: Low, Moderate, and Severe. For each patient, 2 different body positions have been used to collect 2 ECG signals. Then, from each collected signal, 10 non-linear features (Energy, Approximate Entropy, Logarithmic Entropy, Shannon Entropy, Hurst Exponent, Lyapunov Exponent, Higuchi Fractal Dimension, Katz Fractal Dimension, Correlation Dimension and Detrended Fluctuation Analysis) were extracted every 1s ECG time-series length to serve as entries for 19 Machine learning classifiers within a leave-one-out cross-validation procedure. Four different classification scenarios were tested: Low vs. Moderate, Low vs. Severe, Moderate vs. Severe and one Multi-class comparison (All vs. All). Results: The classification report results were: (1) Low vs. Moderate - 100% of Accuracy and 100% of F1–Score; (2) Low vs. Severe - Accuracy of 91.67% and an F1–Score of 94.92%; (3) Moderate vs. Severe - Accuracy of 94.12% and an F1–Score of 96.43%; and (4) All vs All - 78.57% of Accuracy and 84.75% of F1–Score. Conclusion: The results indicate that the applied methodology could be considered a good tool for distinguishing COVID-19’s different severity stages using ECG signals. Significance: The findings highlight the potential of ECG as a fast and effective tool for COVID-19 examination. In comparison to previous studies using the same database, this study shows a 7.57% improvement in diagnostic accuracy for the All vs All comparison.

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Pordeus, D., Ribeiro, P., Zacarias, L., de Oliveira, A., Marques, J. A. L., Rodrigues, P. M., Leite, C., Neto, M. A., Peixoto, A. A., & do Vale Madeiro, J. P. (2023). Training Strategies for Covid-19 Severity Classification. In I. Rojas, O. Valenzuela, F. Rojas Ruiz, L. J. Herrera, & F. Ortuño (Eds.), Bioinformatics and Biomedical Engineering (pp. 514–527). Springer Nature Switzerland. https://doi.org/10.1007/978-3-031-34953-9_40

The COVID-19 pandemic has posed a significant public health challenge on a global scale. It is imperative that we continue to undertake research in order to identify early markers of disease progression, enhance patient care through prompt diagnosis, identification of high-risk patients, early prevention, and efficient allocation of medical resources. In this particular study, we obtained 100 5-min electrocardiograms (ECGs) from 50 COVID-19 volunteers in two different positions, namely upright and supine, who were categorized as either moderately or critically ill. We used classification algorithms to analyze heart rate variability (HRV) metrics derived from the ECGs of the volunteers with the goal of predicting the severity of illness. Our study choose a configuration pro SVC that achieved 76% of accuracy, and 0.84 on F1 Score in predicting the severity of Covid-19 based on HRV metrics.

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Last update from database: 4/19/25, 5:01 AM (UTC)

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