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In 2020, the World Health Organization declared the Coronavirus Disease 19 a global pandemic. While detecting COVID-19 is essential in controlling the disease, prognosis prediction is crucial in reducing disease complications and patient mortality. For that, standard protocols consider adopting medical imaging tools to analyze cases of pneumonia and complications. Nevertheless, some patients develop different symptoms and/or cannot be moved to a CT-Scan room. In other cases, the devices are not available. The adoption of ambulatory monitoring examinations, such as Electrocardiography (ECG), can be considered a viable tool to address the patient’s cardiovascular condition and to act as a predictor for future disease outcomes. In this investigation, ten non-linear features (Energy, Approximate Entropy, Logarithmic Entropy, Shannon Entropy, Hurst Exponent, Lyapunov Exponent, Higuchi Fractal Dimension, Katz Fractal Dimension, Correlation Dimension and Detrended Fluctuation Analysis) extracted from 2 ECG signals (collected from 2 different patient’s positions). Windows of 1 second segments in 6 ways of windowing signal analysis crops were evaluated employing statistical analysis. Three categories of outcomes are considered for the patient status: Low, Moderate, and Severe, and four combinations for classification scenarios are tested: (Low vs. Moderate, Low vs. Severe, Moderate vs. Severe) and 1 Multi-class comparison (All vs. All)). The results indicate that some statistically significant parameter distributions were found for all comparisons. (Low vs. Moderate—Approximate Entropy p-value = 0.0067 < 0.05, Low vs. Severe—Correlation Dimension p-value = 0.0087 < 0.05, Moderate vs. Severe—Correlation Dimension p-value = 0.0029 < 0.05, All vs. All—Correlation Dimension p-value = 0.0185 < 0.05. The non-linear analysis of the time-frequency representation of the ECG signal can be considered a promising tool for describing and distinguishing the COVID-19 severity activity along its different stages.
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A growing number of people are becoming aware of the environmental footprint that our actions have on the environment. Research indicates that a key factor leading to the adoption of an electric vehicle is consumers’ high environmental concern. Indeed, the environmental concern (EC) construct is commonly associated with the purchase of sustainable and eco-friendly products in literature. Our study challenges this assumption. We examined how the environmental factor influenced the behavioral intention of Macau residents to adopt battery-electric vehicle (BEV) technology. For this purpose, we conducted a study based on the UTAUT-2 framework and used structural equation modeling (SmartPLS) to analyze the data. As a result, the choice of vehicles did not depend on the consumers’ level of concern. It appeared that consumers strongly perceived the benefits of a cleaner environment, however, when it comes to technology, environmental benefits are nice to have, rather than the primary incentive to purchase BEVs. Researchers should consider the role of environmental concern as a background factor in technology acceptance models, rather than a direct predictor of behavior. It is also recommended that marketers correctly consider this element when developing their product communications strategies, to appeal to the desired segment of customers.
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In recent years, the integration of Machine Learning (ML) techniques in the field of healthcare and public health has emerged as a powerful tool for improving decision-making processes [...]
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The adoption of project management techniques is a crucial decision for corporate governance in construction companies since the management of areas such as risk, cost, and communications is essential for the success or failure of an endeavor. Nevertheless, different frameworks based on traditional or agile methodologies are available with several approaches, which may create several ways to manage projects. The primary purpose of this work is to investigate the adequate project management methodology for the construction industry from a general perspective and consider a case study from Macau. The methodology considered semi-structured interviews and a survey comparing international and local project managers from the construction industry. The interviews indicate that most construction project managers still follow empirical methods with no specific methodology but consider the adoption of traditional waterfall approaches. In contrast, according to the survey, most project managers and construction managers agree that the project's efficacy needs to increase, namely in planning, waste minimization, communication increase, and focus on the Client's feedback. In addition, there seems to be a clear indication that agile methodology could be implemented in several types of projects, including hospitality development projects. A hybrid development approach based on the Waterfall and Agile methodologies as a tool for the project management area may provide a more suitable methodology for project managers to follow.
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The degree of economic integration in the Guangdong-Hong Kong-Macau Greater Bay Area (GBA), as reflected in the mobility of trade and capital flows, has been strengthened by free trade agreements, but obstacles including border effects, capital controls, differences of exchange rate systems and inadequate cross-regional coordination remain. Digital renminbi (e-CNY) has been tested in Shenzhen, a core GBA city since April 2020. If e-CNY is adopted in the GBA, the area will effectively become a single currency zone. Whether the GBA constitutes an “optimum currency area” (OCA) depends on its degree of economic integration. This paper computes real interest rate differential (RID), uncovered interest rate differential (UID) and deviation from purchasing power parity (PPD) of each regional pair based on data of interest rates, exchange rates and price indexes from 2016M2 to 2022M7. All UID, PPD and RID series have means within about 1 percent point from 0, indicating high degrees of financial integration, real integration and economic integration. With the exception of Guangdong-Macau RID, all series are stationary, implying mean-reverting behavior. Hence, the parities are expected to hold both in the short run and in the long run, which is a condition for an OCA in the GBA. Furthermore, the regression analysis finds that the test launch of e-CNY in Shenzhen (adjusted for the COVID-19 outbreak) has significant impacts on all RIDs, Guangdong-Macau PPD and Hong Kong-Macau PPD. With merely two and a half years of test launch, the introduction of e-CNY already had impacts on overall economic integration in the GBA.
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This review article is among the first to examine the new junket regulations in the Macau gaming industry. Particular emphasis is on the legal and regulatory framework governing the junket activity of gaming promoters and their associates. The recent changes to Macau gaming laws have resulted in stronger licensing requirements for local junket participants and precipitated the collapse of the VIP room system in casinos. Furthermore, this article highlights the policy and managerial implications of the current junket environment for the gaming industry in Macau and possibly other regional gaming jurisdictions. The effects of the new legal environment for Macau junkets could also provide insights into the implementation of similar legislation in other jurisdictions.
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Since the beginning of 2020, Coronavirus Disease 19 (COVID-19) has attracted the attention of the World Health Organization (WHO). This paper looks into the infection mechanism, patient symptoms, and laboratory diagnosis, followed by an extensive assessment of different technologies and computerized models (based on Electrocardiographic signals (ECG), Voice, and X-ray techniques) proposed as a diagnostic tool for the accurate detection of COVID-19. The found papers showed high accuracy rate results, ranging between 85.70% and 100%, and F1-Scores from 89.52% to 100%. With this state-of-the-art, we concluded that the models proposed for the detection of COVID-19 already have significant results, but the area still has room for improvement, given the vast symptomatology and the better comprehension of individuals’ evolution of the disease.
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The gold standard to detect SARS-CoV-2 infection considers testing methods based on Polymerase Chain Reaction (PCR). Still, the time necessary to confirm patient infection can be lengthy, and the process is expensive. In parallel, X-Ray and CT scans play an important role in the diagnosis and treatment processes. Hence, a trusted automated technique for identifying and quantifying the infected lung regions would be advantageous. Chest X-rays are two-dimensional images of the patient’s chest and provide lung morphological information and other characteristics, like ground-glass opacities (GGO), horizontal linear opacities, or consolidations, which are typical characteristics of pneumonia caused by COVID-19. This chapter presents an AI-based system using multiple Transfer Learning models for COVID-19 classification using Chest X-Rays. In our experimental design, all the classifiers demonstrated satisfactory accuracy, precision, recall, and specificity performance. On the one hand, the Mobilenet architecture outperformed the other CNNs, achieving excellent results for the evaluated metrics. On the other hand, Squeezenet presented a regular result in terms of recall. In medical diagnosis, false negatives can be particularly harmful because a false negative can lead to patients being incorrectly diagnosed as healthy. These results suggest that our Deep Learning classifiers can accurately classify X-ray exams as normal or indicative of COVID-19 with high confidence.
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Even with more than 12 billion vaccine doses administered globally, the Covid-19 pandemic has caused several global economic, social, environmental, and healthcare impacts. Computer Aided Diagnostic (CAD) systems can serve as a complementary method to aid doctors in identifying regions of interest in images and help detect diseases. In addition, these systems can help doctors analyze the status of the disease and check for their progress or regression. To analyze the viability of using CNNs for differentiating Covid-19 CT positive images from Covid-19 CT negative images, we used a dataset collected by Union Hospital (HUST-UH) and Liyuan Hospital (HUST-LH) and made available at the Kaggle platform. The main objective of this chapter is to present results from applying two state-of-the-art CNNs on a Covid-19 CT Scan images database to evaluate the possibility of differentiating images with imaging features associated with Covid-19 pneumonia from images with imaging features irrelevant to Covid-19 pneumonia. Two pre-trained neural networks, ResNet50 and MobileNet, were fine-tuned for the datasets under analysis. Both CNNs obtained promising results, with the ResNet50 network achieving a Precision of 0.97, a Recall of 0.96, an F1-score of 0.96, and 39 false negatives. The MobileNet classifier obtained a Precision of 0.94, a Recall of 0.94, an F1-score of 0.94, and a total of 20 false negatives.
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In the paper carried out by Wenjun et al. [Phys. Rev. A 95, 032124 (2017)], a generalization of the James effective dynamics theory based on a first version of the James method was presented. However, we contend that this is not a very rigorous way of deriving the effective third-order expansion for an interaction Hamiltonian with harmonic time-dependence. In fact, here we show that the third-order Hamiltonian obtained by Wenjun et al. is not Hermitian for general situations when we consider time dependence. Its non-Hermitian nature arises from the foundation of the theory itself. In this comment paper, the most general expression of the effective Hamiltonian expanded up to third order is obtained. Our derived effective Hamiltonian is Hermitian even in situations where we have time dependence.
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The continuous development of robust machine learning algorithms in recent years has helped to improve the solutions of many studies in many fields of medicine, rapid diagnosis and detection of high-risk patients with poor prognosis as the coronavirus disease 2019 (COVID-19) spreads globally, and also early prevention of patients and optimization of medical resources. Here, we propose a fully automated machine learning system to classify the severity of COVID-19 from electrocardiogram (ECG) signals. We retrospectively collected 100 5-minute ECGs from 50 patients in two different positions, upright and supine. We processed the surface ECG to obtain QRS complexes and HRV indices for RR series, including a total of 43 features. We compared 19 machine learning classification algorithms that yielded different approaches explained in a methodology session.
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COVID-19 is a respiratory disorder caused by CoronaVirus and SARS (SARS-CoV2). WHO declared COVID-19 a global pandemic in March 2020 and several nations’ healthcare systems were on the verge of collapsing. With that, became crucial to screen COVID-19-positive patients to maximize limited resources. NAATs and antigen tests are utilized to diagnose COVID-19 infections. NAATs reliably detect SARS-CoV-2 and seldom produce false-negative results. Because of its specificity and sensitivity, RT-PCR can be considered the gold standard for COVID-19 diagnosis. This test’s complex gear is pricey and time-consuming, using skilled specialists to collect throat or nasal mucus samples. These tests require laboratory facilities and a machine for detection and analysis. Deep learning networks have been used for feature extraction and classification of Chest CT-Scan images and as an innovative detection approach in clinical practice. Because of COVID-19 CT scans’ medical characteristics, the lesions are widely spread and display a range of local aspects. Using deep learning to diagnose directly is difficult. In COVID-19, a Transformer and Convolutional Neural Network module are presented to extract local and global information from CT images. This chapter explains transfer learning, considering VGG-16 network, in CT examinations and compares convolutional networks with Vision Transformers (ViT). Vit usage increased VGG-16 network F1-score to 0.94.
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The question of how to adequately integrate environment and labor provisions in free trade agreements is still a difficult one for both States and academicians. This article explores China’s approach to environment and labor issues in free trade agreements. For reference and comparison, it relies on the European Union’s and the United States’ approaches in their respective FTAs. The article identifies China’s preference for a case-by-case approach to the inclusion of environmental chapters in its FTAs. Additionally, in most FTAs it avoids to include provisions on labor standards. These two preferences represent major divergences from the European Union’s and the United States’ approaches, characterized by inclusion of chapters on environment and labor in all their modern FTAs. The article also finds that China’s FTAs rely solely on consultations and cooperation for the implementation of environmental and labor provisions, within the framework of Joint Committees and avoid the inclusion of civil society mechanisms. Moreover, resolution of disputes relies exclusively on consultations, in a diverse procedure than the one applicable to trade disputes. Despite alignment with the European Union model, this is another major point of divergence with the United States’ model, which applies the same enforcement mechanism for both environment and labor issues and trade issues and includes the possibility of applying sanctions. Finally, the article concludes that China’s options with regards to the treatment of environment and labor concerns in its free trade agreements aligns with both its domestic governance approach and its approach to international cooperation.
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This paper examines the extent to which China’s aid policies integrate poverty alleviation as a goal of their aid in general, particularly in Guinea. More specifically, the paper analyzed how aid donors focus on poverty alleviation and which policies and mechanisms are in place to address poverty in the countries receiving aid. Regarding the methodology, the author collected data from secondary sources, including government declarations of donors, policy documents at both the donor and recipient levels, as well as from scholarly publications. The following findings resulted from study: China’s aid policies have progressively incorporated poverty alleviationobjectives and identified sectors for intervention against poverty. However, the limitations of China approach to poverty is that China adopts a top-down approach to poverty reduction and lacks of an impact evaluation mechanism based on poverty alleviation.
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This Practice Note considers challenges to the jurisdiction of arbitral tribunals under the Macau Arbitration Law, the scope of challenge before national courts and tribunals.
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Over the past several decades, the dichotomy between traditional and emerging donors has been based upon the notion that emerging donors (such as China) support authoritarian regimes and use foreign aid to pursue their economic interests at the expense of the poor in the recipient countries. Accordingly, Western donors, media, and scholars portray Chinese aid as non-poverty-focused. This study aims to review and analyze whether the dichotomy between traditional and emerging donors is still relevant in the current aid system and to propose a new and rigorous criterion for recategorizing donors. In terms of methodology, this study relies on secondary data, including scholarly works on traditional and emerging donors and foreign aid policy documents. Conclusions based on the research indicate that the divide between traditional donors and (re)emerging donors is becoming more ambiguous. The literature review indicates that the two donors’ aids had a mixed impact and that their approaches were similar. This paper highlights the importance of developing different recategorization criteria depending on the impact of aid.
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The following Arbitration practice note provides comprehensive and up to date legal information on Arbitration as a dispute resolution method in Macau
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