Your search
Results 968 resources
-
Uptake and depuration kinetics of 4,4′-dichlorobenzophenone (main metabolite of dicofol) in the edible clam Meretrix meretrix were evaluated through a mesocosm experiment. M. meretrix was exposed to different dicofol concentrations (environmental concentration, D1 = 50 ng/L; supra-environmental concentration, D2 = 500 ng/L) for 15 days, followed by the same depuration period. To accomplish this goal, an analytical method was successfully optimized for 4,4′-DCBP using QuEChERS as extraction method with a range of concentrations 0.3–76.8 ng/g ww quantified by gas chromatography coupled to tandem mass spectrometry. Our results demonstrated different kinetics of accumulation depending on the two dicofol treatments. For D1, the uptake kinetic was best fitted using a plateau followed by one phase association kinetic model, while for D2 a one phase association kinetic model suited better. Similar bioconcentration factors were obtained for both concentrations but only animals exposed to D2, showed 4,4′-DCBP levels above the limits of quantification after 24 h exposure. These animals also showed lower uptake rate (ku) than organisms exposed to D1. During the depuration period, only organisms exposed to D1 successfully depurated after 24 h. On the other hand, although animals exposed to D2 presented higher elimination factor, they did not reach the original levels after depuration. Moreover, values detected in these clams were higher than the Maximum Residue Level (10 ng/g) established by the European legislation. This indicates that longer periods of depuration time than the ones used in this study, may be needed in order to reach safe levels for human consumption. This work also demonstrated that studies on metabolite kinetics during uptake/depuration experiments, could be a new alternative to understand the impact and metabolism of pesticides in the marine environment.
Explore
USJ Theses and Dissertations
-
Doctorate Theses
(35)
- Faculty of Art and Humanities (10)
- Faculty of Business and Law (9)
-
Faculty of Health Sciences
(1)
- Psychology (1)
- Faculty of Religious Studies and Philosophy (2)
- Institute for Data Engineering and Science (2)
-
Institute of Science and Environment
(1)
- Science (1)
-
School of Education
(10)
- Education (10)
-
Master Dissertations
(563)
- Faculty of Arts and Humanities (38)
-
Faculty of Business and Law
(333)
- Business Administration (270)
- Community Development (9)
- Government Studies (54)
- Faculty of Health Sciences (108)
-
Faculty of Religious Studies and Philosophy
(8)
- Philosophy (1)
- Religious Studies (7)
- Institute of Science and Environment (11)
-
School of Education
(67)
- Education (67)
Academic Units
-
Faculty of Arts and Humanities
(138)
- Álvaro Barbosa (25)
- Carlos Caires (4)
- Filipa Martins de Abreu (5)
- Filipa Simões (1)
- Filipe Afonso (6)
- Francisco Vizeu Pinheiro (10)
- Gérald Estadieu (4)
- José Simões (19)
- Nuno Rocha (1)
- Nuno Soares (16)
- Tania Marques (2)
-
Faculty of Business and Law
(60)
- Alessandro Lampo (3)
- Alexandre Lobo (10)
- Douty Diakite (4)
- Florence Lei (3)
- Jenny Phillips (4)
-
Faculty of Health Sciences
(29)
- Andrew Found (4)
- Angus Kuok (10)
- Cynthia Leong (2)
- Edlia Simoes (2)
- Vitor Santos Teixeira (9)
-
Faculty of Religious Studies and Philosophy
(27)
- Cyril Law (6)
- Edmond Eh (5)
- Franz Gassner (4)
-
Institute of Science and Environment
(59)
- Ágata Alveirinho Dias (20)
- Chan Shek Kiu (4)
- David Gonçalves (17)
- Karen Tagulao (6)
- Raquel Vasconcelos (7)
- Sara Cardoso (4)
- Thomas Lei (2)
-
Macau Ricci Institute
(10)
- Stephen Rothlin (10)
-
School of Education
(57)
- Elisa Monteiro (4)
- Keith Morrison (15)
- Rochelle Ge (7)
Resource type
- Book (23)
- Book Section (48)
- Conference Paper (69)
- Encyclopedia Article (1)
- Film (1)
- Journal Article (168)
- Magazine Article (5)
- Presentation (14)
- Report (42)
- Thesis (596)
- TV Broadcast (1)