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This paper presents an algorithm that applies metrics derived from automatic QRS detection and segmentation in electrocardiogram signals for analyzing Heart Rate Variability to study the evolution of metrics in the frequency domain of a clinical procedure. The analysis was performed on three sets of elderly people, who are categorized according to frailty phenotype. The first set was comprised of frail elderly, the second pre-frail elderly, and the third robust elderly. Investigators from many disciplines have been encouraged to contribute to the understanding of molecular and physiological changes in multiple systems that may increase the vulnerability of frail elderly. In this work, the frailty phenotype can be characterized by unintentional weight loss, as self-reported, fatigue assessed by self-report, grip strength (measured directly), physical activity level assessed by self-report and gait speed (measured). The results obtained demonstrate the existence of significant differences between Heart Rate Variability metrics for the three groups, especially considering a higher preponderance for sympathetic nervous system for the group of robust patients in response to postural maneuver.

There are many systematic reviews on predicting stock. However, each of them reveals a different portion of the hybrid AI analysis and stock prediction puzzle. The principal objective of this research was to systematically review and conclude the systematic reviews on AI and stock to provide particularly useful predictions for making future strategies for stock markets. Keywords that would fall under the broad headings of AI and stock prediction were looked up in two databases, Scopus and Web of Science. We screened 69 titles and read 43 systematic reviews which include more than 379 studies before retaining 10 of them.

Consumers' selections and decision-making processes are some of the most exciting and challenging topics in neuromarketing, sales, and branding. Multicultural influences and societal conditions are also crucial aspects to consider from a global perspective. Applying neuroscience tools and techniques in international marketing and consumer behavior is an emergent and multidisciplinary field that aims to understand consumers' thoughts, reactions, and selection processes in branding and sales. This study focuses on real-time monitoring of different physiological signals using eye-tracking, facial expressions recognition, and Galvanic Skin Response (GSR) acquisition methods to analyze consumers' responses, detect emotional arousal, measure attention or relaxation levels, analyze perception, consciousness, memory, learning, motivation, preference, and decision-making. The primary purpose of this research was to monitor human subjects' reactions to these signals during an experiment designed in three phases consisting of different types of branding advertisements. The non-advertisement exposition was also monitored during the gathering of survey responses at the end of each phase. A feature extraction module was implemented with a data analytics module to calculate statistical metrics and decision-making supporting tools based on Principal Component Analysis (PCA) and Feature Importance (FI) determination based on the Random Forest technique. The results indicate that when compared to image ads, video ads are more effective in attracting consumers' attention and creating more emotional arousal.

Neuromarketing lies at the intersection of three main disciplines: psychology, neuroscience, and marketing, and it has been a successful neuroscientific approach for the study of real-life choices such as consumer behavior [1]. A current gap in the cosmetics field is the lack of published research studies, considering the marketing investment done yearly in this category. With the rapid economic expansion and the rise of social media in China, consumers' interest in beauty is growing. Even though the Chinese cosmetics sector is rapidly expanding, no studies have been done with Chinese consumers. This study aims to employ the same approach as previously done in consumer neuroscience studies to evaluate cosmetic brands' marketing strategy to understand better if immediate emotional responses can be measured using Electrodermal Activity (EDA). Here, we focus on cosmetics products advertisement as a model to understand consumer preference formation and choice. Eighteen Chinese female consumers were recruited between 19 and 37 years old. From the results obtained, it was understood that none of the participants have voted for the product advertisement for which they showed higher emotional arousal. However, it appears that the participants' preference is for the products for which the brand awareness is stronger since the product advertisements with more votes are the ones for the Korean brand used. The product advertisements with Asian faces were the ones with more votes, suggesting that Asian faces have engaged consumer preference. However, the product advertisements for the Brazilian brands, unknown to the Chinese public, were the ones with fewer votes, although, those product advertisements were the ones with more emotional arousal per minute. Those advertisements were also those with non-Asian faces, suggesting that this feature influenced voting decisions. From this study, it has been observed that Electrodermal Activity is a measure of emotional arousal that by itself cannot be translated into consumer engagement. Therefore, it is also proposed to evaluate brand awareness in future studies related to product advertisements. The physical features of the people included in the advertisements is also suggested to be further evaluated in future studies since a different cultural background seems to influence the consumers' engagement. Furthermore, using EDA to complement other neurophysiological tools like facial expression analysis is also suggested for future studies to have evidence about the nature of the emotions raised.

Covid-19 has hit the world unprepared, as the deadliest pandemic of the century. Governments and authorities, as leaders and decision makers fighting against the virus, enormously tap on the power of AI and its data analytics models for urgent decision supports at the greatest efforts, ever seen from human history. This book showcases a collection of important data analytics models that were used during the epidemic, and discusses and compares their efficacy and limitations. Readers who from both healthcare industries and academia can gain unique insights on how data analytics models were designed and applied on epidemic data. Taking Covid-19 as a case study, readers especially those who are working in similar fields, would be better prepared in case a new wave of virus epidemic may arise again in the near future.

Fast and efficient malaria diagnostics are essential in efforts to detect and treat the disease in a proper time. The standard approach to diagnose malaria is a microscope exam, which is submitted to a subjective interpretation. Thus, the automating of the diagnosis process with the use of an intelligent system capable of recognizing malaria parasites could aid in the early treatment of the disease. Usually, laboratories capture a minimum set of images in low quality using a system of microscopes based on mobile devices. Due to the poor quality of such data, conventional algorithms do not process those images properly. This paper presents the application of deep learning techniques to improve the accuracy of malaria plasmodium detection in the presented context. In order to increase the number of training sets, deep convolutional generative adversarial networks (DCGAN) were used to generate reliable training data that were introduced in our deep learning model to improve accuracy. A total of 6 experiments were performed and a synthesized dataset of 2.200 images was generated by the DCGAN for the training phase. For a real image database with 600 blood smears with malaria plasmodium, the proposed Deep Learning architecture obtained the accuracy of 100% for the plasmodium detection. The results are promising and the solution could be employed to support a mass medical diagnosis system.

This book offers an objective and dispassionate analysis of modern educational architecture allowing us to notice gaps. The fundamental question addressed is whether our education system will embrace knowledge-based society and have the foresight to better prepare future generations. If educators around the world step back for a moment, it is not difficult to notice that unanswered questions about education are looming everywhere. The existent academic literature on education is abundant and embracing. In consequence, one can ask why is this book necessary? Indeed, this book is the result of senior university professors sharing their learnings and anticipating the pivotal issues facing all education professionals. According to the United Nations, by 2050, 68% of the world’s population will be living in urban areas. This fact cannot be ignored as it is one of the drivers of the profile of the future students. The reasons to organize this publication are many, but among them three stand out which also function as the driving forces behind this project: (1) University professors teach future generations based on models grounded on knowledge advanced by past experiences; (2) The decisive requirement to understand the needs of the new generations of university millennial students; and (3) What are the critical challenges of global societies? "This book problematizes the issues concerning education, and its main contribution is to answer the need to rethink education, face contemporary challenges, and reorganize the way public policies address education. It critically analyses the challenges of global societies in a decentralized perspective, not only reflecting a western perspective of education and knowledge production. The project's originality comes from the contemporaneity of the topics covered, from the interdisciplinary perspective, and from the specific attention given to trends around education." —Cátia Miriam Costa, Researcher and Invited Assistant Professor, Centre for International Studies, Perfil Ciência

Macao is well known for its gaming industry. However, there are also many traditional small-to-medium enterprises which are family-owned and run. There is no doubt that social capital is one of the key competitive advantages that family businesses possess, particularly when it comes to Chinese businesses with strong family values that emphasize the importance of trustworthiness and guanxi (relationships). As opposed to other forms of capital, social capital cannot be passed from one generation to another through the will of the incumbents. So, how is social capital passed on in family businesses from one generation to the next? Based on an in-depth study of five cases of successful family businesses in Macao, this research identified the forms of social capital present in business families and the succession process of these firms. From the generalizations drawn from the five cases, a theoretical framework is proposed to understand the intergenerational transmission of social capital in Chinese family businesses

The world is perpetually changing, and the COVID-19 pandemic has taught us that the future is full of unforeseen challenges and potentialities. What are the implications of the advancement in technology on education? How are teachers coping with contemporary educational expectations? Is there a need to redesign the learning environment? What is the exact nature of the forces driving such a change? Is there anything we can learn from successful innovations around the globe? The goals of this dissertation include designing a learning/teaching app and redesigning classroom furniture for primary-level education. A design thinking methodology is used, working through the phases of empathizing, defining, ideating, prototyping and testing the two potential designs

In the light of the many kinds of journeys that have been considered pilgrimages, this book uses phenomenology as a method to examine the claim that pilgrimage is a journey to the ‘center’ during which pilgrims seek meaning s for themselves. First, by analyzing a phenomenology of Christian pilgrimage, this work attempts to identify what commonalities, as well as differences, exist between Christian pilgrimage and secular pilgrimage in terms of ‘natural attitude’. Next, by using a phenomenological method, such as transcendental reduction, the distinction between these two types of pilgrimage could be clarified that the happiness sought in Christian pilgrimage is both intentionally spiritual and sustainable, while primarily intellectual or sensory in secular pilgrimage. Lastly, this work seeks to establish whether or not ‘being at leisure’ is the primary element for pilgrims whose aim is to attain an understanding of happiness during a pilgrimage

<abstract><p>About 6.5 million people are infected with Chagas disease (CD) globally, and WHO estimates that $ &gt; million people worldwide suffer from ChHD. Sudden cardiac death (SCD) represents one of the leading causes of death worldwide and affects approximately 65% of ChHD patients at a rate of 24 per 1000 patient-years, much greater than the SCD rate in the general population. Its occurrence in the specific context of ChHD needs to be better exploited. This paper provides the first evidence supporting the use of machine learning (ML) methods within non-invasive tests: patients' clinical data and cardiac restitution metrics (CRM) features extracted from ECG-Holter recordings as an adjunct in the SCD risk assessment in ChHD. The feature selection (FS) flows evaluated 5 different groups of attributes formed from patients' clinical and physiological data to identify relevant attributes among 57 features reported by 315 patients at HUCFF-UFRJ. The FS flow with FS techniques (variance, ANOVA, and recursive feature elimination) and Naive Bayes (NB) model achieved the best classification performance with 90.63% recall (sensitivity) and 80.55% AUC. The initial feature set is reduced to a subset of 13 features (4 Classification; 1 Treatment; 1 CRM; and 7 Heart Tests). The proposed method represents an intelligent diagnostic support system that predicts the high risk of SCD in ChHD patients and highlights the clinical and CRM data that most strongly impact the final outcome.</p></abstract>

Nowadays, the increasing number of medical diagnostic data and clinical data provide more complementary references for doctors to make diagnosis to patients. For example, with medical data, such as electrocardiography (ECG), machine learning algorithms can be used to identify and diagnose heart disease to reduce the workload of doctors. However, ECG data is always exposed to various kinds of noise and interference in reality, and medical diagnostics only based on one-dimensional ECG data is not trustable enough. By extracting new features from other types of medical data, we can implement enhanced recognition methods, called multimodal learning. Multimodal learning helps models to process data from a range of different sources, eliminate the requirement for training each single learning modality, and improve the robustness of models with the diversity of data. Growing number of articles in recent years have been devoted to investigating how to extract data from different sources and build accurate multimodal machine learning models, or deep learning models for medical diagnostics. This paper reviews and summarizes several recent papers that dealing with multimodal machine learning in disease detection, and identify topics for future research.

Since the beginning of 2020, Coronavirus Disease 19 (COVID-19) has attracted the attention of the World Health Organization (WHO). This paper looks into the infection mechanism, patient symptoms, and laboratory diagnosis, followed by an extensive assessment of different technologies and computerized models (based on Electrocardiographic signals (ECG), Voice, and X-ray techniques) proposed as a diagnostic tool for the accurate detection of COVID-19. The found papers showed high accuracy rate results, ranging between 85.70% and 100%, and F1-Scores from 89.52% to 100%. With this state-of-the-art, we concluded that the models proposed for the detection of COVID-19 already have significant results, but the area still has room for improvement, given the vast symptomatology and the better comprehension of individuals’ evolution of the disease.

Robotics are being used in the intervention with children with Autism Spectrum Disorder (ASD) in many places and already for many years. Many robots were developed and different studies are being made in order to evaluate its effectiveness. “Socially Assistive Robotics” is shown to be effective in different areas mainly in social and emotional development. Milo, a robot developed by a team led by Richard Margolin for the Robots4Autism program (RoboKind, 2020), is one of the robots whose use is reported to be successful. In Macao there is no report of studies or experiences on the use of robots in the intervention with children with ASD. In a collaboration between the Macao Science Centre, the Macao Autism Association (MAA) and the University of Saint Joseph, an exploratory study was developed to understand the applicability of Milo to the work with children with ASD in Macao. The study showed that the robot is able to facilitate social and emotional competences of children with ASD. However, several limitations including language, cultural differences, the inexperienced facilitators and the level of sessions are too simple for the participants to be aware of that may affect the effectiveness of the intervention. It is important to show that the adoption of Milo in Macao for intervening children with ASD can be further implemented, with better practical solutions.

The main focus of this thesis was to characterize the patient information leaftlets as a text genre in Portugal, compare it with the same text genre in other countries and propose a new form of elaborating these documents in order to rise its comprehensibility levels. Therefore, we proceeded with an analysis of the patient information leaflet as a text genre and its relationship with text linguistics and translation. We also analyzed a corpus of 50 patient information leaflets with focus not only on its content, but also in the way they were created. In order to know the opinion of the general public, a survey about the situation of these documents in Portugal was distributed. In order to find the differences between these documents in different contexts, we made a comparison of a portuguese leaflet with leaflets from other countries. By last, we proposed a new writing scheme for these documents, reformulating one of the leaflets analyzed in the corpus and, to get the opinion of the general public, distributing a survey where the reformulated version was compared to the original one. The results point out to a lack of uniformity between documents and the way that they are created in pharmaceutical companies. The content of the patient informations leaflets in Portugal has an excess of text, technical language and a visual organization that is not appealing, problems that were also pointed out by the public in a survey. In the comparison between leaflets of different countries, big differences were found even when they were produced by the same company. When confronted with the original version and the reformulated version of the same document, the general public prefered the latter.

Este trabalho consiste numa análise multimodal das estratégias discursivas de Bernie Sanders e Hillary Clinton num excerto de um debate sobre as benesses dadas pela senadora norte americana aos bancos no pós-crise económica global de 2008. Bernie Sanders e Hillary Clinton evidenciaram uma linguagem corporal diferente, tanto na posição de locutor como na de interlocutor. No entanto, mesmo utilizando estratégias de comunicação verbal e física diferentes, os gestos utilizados enquadram-se no campo dos gestos recorrentemente observados em figuras políticas em estudos feitos por outros autores. Reforça-se assim a ideia de que os gestos em questão são regularmente utilizados por figuras políticas.

This paper is motivated by two observations in the large civil aircraft (LCA) industry. (1) Boeing and Airbus are significantly different in the degree of offshoring. (2) The degree of offshoring also changes among different aircraft models. To offer an explanation, this paper focuses on issues related to fragmentation. Existing literature has established the tie between fragmented technology and offshoring. However, it is assumed that production can be fragmented readily and at no cost; and only exogenous global economic factors have impact on the degree of fragmentation. This model distinguishes itself from others by incorporating endogeneity in fragmentation. A final-good firm can spend on R&D specifically for its own fragmented technology. As a result, the final-good firm can optimally choose the portion of components to be offshored. A strategic trade policy model is used to show that the degree of offshoring depends on the firm's own cost of production, the host country's cost of production, the global state of technology as well as the government trade policies. In particular, export subsidy and subsidy on R&D of fragmented technology are shown to be policy substitutes. Keywords: Fragmentation; Offshoring; Outsourcing; Aircraft; Export subsidy; R&D subsidy; Boeing; Airbus JEL classification: F12; F13; F23; L13

Objective: As a world tourist destination, Macao is inevitably under the impact of the COVID-19 pandemic. However, the market of integrated resorts in Macao are shared by only a few casino concessionaries, together forming an oligopoly. While the firms attempted to adjust price, quantity and quality of their hotel services in response to the pandemic, they could not overlook the strategic interactions with other players in the market. Hence, this paper aims to investigate the possible impact of the pandemic on the oligopolistic strategies in the integrated resort market in Macao. Methodology: Application of a theoretical model of differentiated oligopoly to this six-firm case shows that price differences across firms depend on their quality differentiation. In order to analyze these price differences empirically, this paper collects data of hotel room rates of the integrated resorts from November, 2019 to mid-August, 2020, covering the periods before and after the outbreak of COVID-19. Originality: In the existing literature, there is a lack of studies of the oligopoly in the hospitality industry of Macao. Furthermore, the effect of COVID-19 is still ongoing, so this present paper is one of the first to perform such analysis. Results: The regression of each of the hotel price differentials on the COVID-19 dummy variable shows that COVID-19 has statistically significant impacts on almost all the price differentials. Intuitively, MGM and Wynn were in the high-price segment before and after the outbreak, while other firms switched positions in the low-price segment during the pandemic. One obvious downstream movement was by Conrad. According to the proposition derived from the theory, these imply that COVID-19 should have significant impact on the quality differentiation of the firms. Practical implications: The results are in line with the observations that the integrated resorts have rolled out staycation packages according to preferences of local residents. These quality adjustments observed in Macao’s hospitality industry currently only involved variable inputs rather than fixed inputs of production; therefore, the impact of COVID-19 should be seen as short-term effects. Keywords: Covid-19; Differentiated oligopoly; Hospitality industry; Hotel room rate; Oligopolistic market structure; Pricing strategy.